We would like to cordially invite you to attend the BCRT Lecture Series 2015
“Linked in regeneration” wants to join young and senior scientists from Berlin to come together and discuss with internationally renowned guest speakers how to advance research into regenerative medicine and its translation into the clinics. The BCRT lecture series is organized and hosted by young postdocs of the graduate school of the BCRT.

Speaker: Marc McKee

(McGill University - Montreal)

Host: Guido Moll (BSRT Postdoc)

This lecture takes place at 17:00 as a double within the topic Dissecting Disease mechanisms using models of tissue regeneration and biomineralisation. The other lecture by Prof. Josef Penninger is at 16:00.

Harnessing biology’s

mineralization strategies

for regenerative therapy

Research in Professor McKee’s laboratory is primarily focused on mineralization (calcification) of extracellular matrices in bones and teeth, and in other biomineralizing systems such as inner-ear otoconia and eggshells. In particular, they are investigating the role of mineral-binding proteins in normal mineralization and pathologic mineralization as seen in urolithiasis (kidney stones), arthritis and vascular calcification (including atherosclerosis). We study how biomineralization is regulated by investigating the control of the phosphate/pyrophosphate balance in extracellular matrices by alkaline phosphatase and other pyrophosphate-handling proteins, and by investigating how extracellular matrix proteins and enzymes control mineral crystal growth.

Click here for profile of Marc McKee

Three interesting publications

Molecular determinants of extracellular matrix mineralization in bone and blood vessels.

[Click here for PubMed]

Spontaneous calcification of arteries and cartilage in mice lacking matrix GLA protein.

[Click here for PubMed]

Intracellular precipitation of hydroxyapatite mineral and implications for pathologic calcification.

[Click here for PubMed]

Venue:
Auditorium 0.0045

Berlin Brandenburg Center for Regenerative Therapies (BCRT)

Charité | Campus Virchow Klinikum

Föhrer Str. 15 | 13353 Berlin

More Information: www.b-crt.de/das-zentrum/veranstaltungen/bcrt-lecture-series/

Kindly supported by the "Verein der Freunde und Förderer der Berliner Charité e.V."